An Observational Study on Etiology of Proteinuria in Postrenal Transplant Recipients in a Tertiary Hospital of North India
Published: 2024-06-04
Page: 45-52
Issue: 2024 - Volume 7 [Issue 1]
Gigin SV *
Department of Nephrology, SMS Medical Collage, Jaipur, Rajasthan, India.
Dhananjai Agarwal
Department of Nephrology, SMS Medical Collage, Jaipur, Rajasthan, India.
Pankaj Beniwal
Department of Nephrology, SMS Medical Collage, Jaipur, Rajasthan, India.
Rakesh Gupta
Department of Nephrology, SMS Medical Collage, Jaipur, Rajasthan, India.
*Author to whom correspondence should be addressed.
Abstract
The presence of proteinuria from native kidneys is hard to interpret when detected after transplantation. Studies show that pre-transplant proteinuria, even within the nephrotic range, abruptly reduces during the first weeks after receiving a normal functioning kidney transplant. Immunosuppressive medications, such as calcineurin inhibitors (e.g., cyclosporine, tacrolimus), can cause nephrotoxicity and result in proteinuria. Urinary tract infections (UTIs), can cause proteinuria. Studies have found that proteinuria doubled the risk of graft failure in comparison with non proteinuric transplant recipients Risk for death was almost twice as high for patients with proteinuria at 1 year.
Keywords: Proteinuric transplant recipients, proteinuria, kidney transplant, kidney transplantation