Worsening Hypothyroidism in a Patient with Nephrotic Syndrome - A Case Report
Vaibhav J. Mehta *
Department of Medicine, SBKS Medical College, Vadodara, Gujarat, India.
Tharun Rao Nagula
Department of Medicine, SBKS Medical College, Vadodara, Gujarat, India.
Darsh G. Vaghani
Department of Medicine, SBKS Medical College, Vadodara, Gujarat, India.
Aarjuv Majmundar
Department of Medicine, SBKS Medical College, Vadodara, Gujarat, India.
Sanjay Rathwa
Department of Medicine, SBKS Medical College, Vadodara, Gujarat, India.
Rajesh Sumple
Department of Medicine, SBKS Medical College, Vadodara, Gujarat, India.
*Author to whom correspondence should be addressed.
Abstract
The therapy of patients may be complicated by the coexistence of nephrotic syndrome and hypothyroidism, which might exacerbate the thyroid condition. In this case report, a 55-year-old woman with previously well-controlled hypothyroidism is described. Her symptoms deteriorated as a result of recently discovered nephrotic syndrome. Increased gut edema and urine loss of thyroxine-binding globulin were likely to blame for the hypothyroidism's worsening, as well as changed levothyroxine absorption. The patient's symptoms improved after receiving more levothyroxine and the proper care for nephrotic syndrome, which was shown by lower levels of thyroid-stimulating hormone. This instance highlights the significance of taking nephrotic syndrome into account as a potential reason for patients' hypothyroidism to worsen when they are receiving levothyroxine therapy.
Keywords: Hypothyroidis, nephrotic syndrome, gut edema, urine loss